Revolutionary War officer, Pittsburgh business and civic leader, born in Hillsborough, Ireland. Craig took part in the capture of the Hessians at Trenton on Christmas night 1776, and fought in the battles of Princeton, Brandywine, and Germantown (all 1777); he wintered at Valley Forge (1777-78). Commanding Fort Pitt, Craig led troops to assist George Rogers Clark in the Detroit expedition (1781). Craig was deputy quartermaster general and military storekeeper of Pittsburgh (1791), led federal troops during the Whiskey Rebellion (1794), and helped prepare munitions during War of 1812. 

Craig came to Fort Pitt in 1781. Isaac Craig and his business partner, Stephen Bayard, purchased all of the ground between Fort Pitt and the Allegheny River from John Penn and his son in 1783. Eventually, he purchased the site of Fort Pitt and resided in the blockhouse with his family for several years. After the war, Craig served as deputy quartermaster general and military storekeeper of Pittsburgh and led federal troops in 1794 during the Whiskey Rebellion. 

In February, 1785, Major Craig married Amelia Neville, the only daughter of John Neville, a native of Virginia, and the colonel of one of the Virginia regiments, who was then residing at Woodville, about eight miles from Pittsburgh, and about one half-mile south of the new stone Episcopal Church, on the Washington turnpike. Major Craig had a taste for, and a very respectable knowledge of Mathematics, was an excellent carpenter, and was fond of mechanic art generally, and philosophical experiments; and it was, no doubt, because of this knowledge, and these inclinations, that the American Philosophical Society, in May, 1787, unexpectedly, on his part, complimented him by electing him a member. 

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